Praxis Precision Medicines' ulixacaltamide (PRAX-944) is a potent and selective small molecule T-type Ca2+ channel blocker being developed for the potential treatment of essential tremor. ET is a ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

February 6, 2008 — Results of a large case-control study suggest that current use of calcium-channel blockers, but not other antihypertensive agents, is associated with a significantly reduced risk ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Use of calcium channel blockers (CCBs), particularly cardioselective agents, had a modest but statistically significant association with glaucoma, a large meta-analysis showed. Overall, patients with ...

Please provide your email address to receive an email when new articles are posted on . Beta-blockers more effectively reduce risk for death or hospitalization in people with HFpEF compared with ...

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a ...

Towards the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared on the scene, and practically shut down the world for the next several months. Since then, a slow and ...

Little additional work has been performed beyond that of Lee et al. [1,3,10] to further investigate the proposed dual action of ibutilide. Our laboratory has sought to examine the effects of sodium ...