DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

The herpesvirus can manipulate our DNA with far more precision than previously thought. The virus condenses and changes the shape of our genetic material to hijack the host genes needed for ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...