DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Dr Karsten Eastman, CEO, Sethera Therapeutics, highlights the challenges around ‘true’ diversification in DNA libraries.

A graphic representation of a round, lumpy, blue protein and a single, comblike, purple strand of RNA interacting with a twisted, double, blue strand of DNA that separates where it meets the RNA. A ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...