In this paper, we first recall the three restrictive hypotheses outside which it is not possible to speak of an optimum, and then we specify in which context (decision aid) this article is located.

To optimize the final formulation for a drug, it must meet many criteria beyond producing a safe and effective product. For example, it must be stable and amenable to various manufacturing steps, such ...

Of the many skills leaders need to be effective, research consistently shows that complex problem solving is paramount. For most of us, however, solving difficult problems and selling the solutions ...