Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular process ...

Thousands of new genes are hidden inside the “dark matter” of our genome. Previously thought to be noise left over from evolution, a new study found that some of these tiny DNA snippets can make ...

Perhaps you’ve read in a biology textbook that humans have the same number of genes as C. elegans, a worm used in scientific research. Perhaps you’d also like to believe that humans are more complex ...

Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this ...

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...