How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 22 (Nov., 1990), pp. 8726-8730 (5 pages) We have cloned and characterized the mtr operon of Bacillus ...
Support for the hypothesis that transcription is initiated before the operator region of the trp-operon of E. coli, and that the repressor, in binding to the operator region, directly blocks the ...